In this episode, Dan and Nate had the opportunity to speak with Dr. Alberto Ortiz Sotomayor, He is a Medical Director for Rehealth, A stem cell therapy facility located in Cancun Mexico.
Dr. Daniel Pozarnsky 0:38
Hello, this is Dr. Daniel Pozarnsky here with Dr. Alberto Ortiz sarcoma from the region clinic in Cancun, Mexico and I’m here in West Fargo, North Dakota at the Balance chiropractic clinic renowned clinic in West Fargo.
Unknown Speaker 1:08
So,
Dr. Daniel Pozarnsky 1:10
Alberto, we’ve talked a few times now and we were just chatting about COVID and how Mexico is starting to open up a little bit more. And that 70% of Mexico is relies upon tourism from, like the United States and you’re up in Canada, I’m assuming I know there’s a lot of Canadians when I travel south to like, at when I’ve been in like Costa Rica, or like the Caribbean like Dominican Republic and stuff like Canadians.
Unknown Speaker 1:52
Yeah, you should have gotten away from winter.
Dr. Daniel Pozarnsky 1:55
It’s always cold in Canada. So, tell me that tell us a little bit about like your background in with regenerative medicine and stem cell therapy, as well as Talk to us a little bit about your clinic. And, and some I have a list of different items that I’m interested in picking your brain about how stem cell therapy may work with like people that have had a significant impact from the Coronavirus or the COVID-19 virus, how stem cells can help people with MS sports injuries, sports injuries and spinal injuries because that’s what I specialize in is the spine will actually all the joints in the body but we Get a lot of people with herniated disk and that can you know, really ruin someone’s life if they have a severe herniated disc or if they have to get fusions and and they lose the range of motion they might not be able to do some of the things they love anymore as far as like possibly golf or running or things that involve jumping or high impact. And it seems to me when I studied stem cell therapy that that is what in the future will prevent a right now at your clinic right now what will what can help prevent that prevent but help heal those people so they can enjoy doing what they love to do?
Unknown Speaker 3:49
Well, once again, thank you for the for the space for the spot and for the trust as well for you and everybody who’s listening to your podcast. And as you’re setting my Name is Humberto and I serve currently I serve as medical director here at the Red Hills regenerative medicine, and what some systematic or some suspending is like the SR clinical free health, where we treat pediatric patients and rehab is mostly aimed for adults. So, my history right here in the clinic, I have been political teen since 2014. And prior to that, I have been working with medical tourism. However, that side was becoming a little bit more, let’s say for me because it was not academically or mentally stupidly.
Dr. Daniel Pozarnsky 4:38
So for like, I’m going to pause you for a second like for people that don’t know, like, what is medical tourism. Some people have a lot of people who haven’t heard that word before.
Unknown Speaker 4:51
Medical Tourism it’s it’s been gaining a lot of fans, whether it is from from the US from Canada, and even parts of Europe in which some form of medical services are provided because they are somehow cheaper here or slightly cheaper, or the insurances covers them here. And also the availability of the services because I don’t know, I don’t know how exactly medical services run in the US and in Canada, I have some idea. But I have not been there in order for me to actually witness it completely. So
Dr. Daniel Pozarnsky 5:27
it’s very complicated, very complicated. You have
Unknown Speaker 5:30
to be at the hospital in order to receive attention. I don’t know how much in advance you have to set an appointment. I don’t know how much Nigeria, I don’t know even for image testing, let’s say imaging is especially if insurance is not going to cover it or partially correlate. That is why medical tourism here at least in the Caribbean, because it’s a destination and touristy destination, a nice place to meet. In the meantime, you’re having whatever procedure or therapy Or evaluation unit. And positive bundles are it may be cheaper or slightly cheaper. I’m not saying that it’s going to be extremely cheap. But in some cases there is there I have met patients that choose availability and readiness instead of just waiting, I don’t know, let’s say six to 10 months to be treated. So uh, and on the other side, one niche of medical tourism that is blooming tremendously. This regenerative medicine and plastic surgery, we are not into plastic surgery. We may be hand in hand, but his one side is aesthetic. And the other one as you know, it’s mostly running relative anti aging healing processes. So that’s that’s pretty much what we’re focusing on aging from a non cosmetic point of view pretty much boosting the immune system helping our patients to deal and cope and even guide through They are experiencing or diagnosed with conditions that currently do not have a cure, or some patients that are giving up on some medication because of the side effects. So that is where we come in and regarding the patient’s Well, that’s a little bit of a different story. I don’t want to dig into into that right now. But it’s pretty much offering an alternative, especially in those cases where they have pretty much exhaustive almost, if not every option that is being offered either by the insurance or the availability or they have
Dr. Daniel Pozarnsky 7:34
doctors in general. Yeah, insurance companies really regulate what doctors can do as well as like the FDA in the United States is a lot more regulated than your or Mexico. So I know a lot of people will go to Central America to get different types of operations done as far as like regenerative medicine or dentistry. And I’ve even I sat next to a lady on a plane like three or four years ago she talked to me the whole time about I don’t think I even said a word. She just talked to you for like three hours straight about her sister who went to Mexico and had both her knees. She’s was a tennis player and she had both her knees injected with stem cells and, and and got plastic surgery while she was. So you may you may as well so yeah, yeah, that does make sense if you if you can get done in the same clinic or the same city. Yeah. And Cancun is pretty Americanized compared to what it used to be. It seems like I was there last year. I was there last year for For a conference and it looked just like any other city in the United States Yeah. Yep. Yep. That is what it’s like. It is kind of like a suburb right there in. In. In red on the right on the beach. of of the city there. Yeah, totally. It’s like the shopping malls and all the hotels. It is basically like suburbia. If when I lived in a bigger city, that’s what it was like. Lots of shopping. So what what has the Coronavirus been like, in Mexico? How has that affected the population? Is it the same as the United States are? Well
Unknown Speaker 9:56
to be honest. How has the The virus been affecting the country, it’s pretty much the same as in the US and in some other countries in Europe. The main difference that you’re going to find is the difference in terms of population or numbers. In some cases is going to be
Unknown Speaker 10:17
the numbers are going to be more
Unknown Speaker 10:21
are going to cause more impact, both in services on employment, diseases, deceased people, and and actual confirmed cases. So eventually, because we received the diagnosis diagnostic kits, later, or late, sorry, yep, but that’s what happened. So the ones that were actually tested with or using a PCR or 80 or something like that. The actual diagnosis takes a while, or at least here in the US, you now have like some form wick testing method and the US. I believe it’s a country that is that has the highest rate of tests.
Dr. Daniel Pozarnsky 11:07
Yeah. And that’s why we have the highest number of cases also. So it’s kind of
Unknown Speaker 11:15
it. I learned from from from a hospital in Miami, I learned that it sounds like tremendous, but also, the overall population in the US is like 300 and something million people right now, if I’m not wrong, so
Dr. Daniel Pozarnsky 11:28
I think so. Yes. Nate, you know, how can you look at the population? Yeah, I would, I would think that we’re not I would think that like China, and where it first started, and really overpopulated countries like even like India, and in different countries like that, probably, or Japan, probably have a lot more cases because they’re more congested with people and that’s why I hope the Internet has got the population. We’re looking for the population of the United States.
Unknown Speaker 12:22
Right now the population
Dr. Daniel Pozarnsky 12:27
328 million is what my intern says here. And I don’t know what the total number of cases is because I try not to look at the numbers because it’s
Yeah.
Yeah, totally. That’s what I tell my patients to because the news puts that up for a rate like, you know, They only broadcast things that are negative mostly so that they can get more viewers. They’re making money off of having the numbers running and having the numbers higher. And and so it’s it’s not healthy for people to watch the numbers and try to figure out this overall stats and try to be at armchair epidemiologist,
Unknown Speaker 13:27
besides, just as I told you, one of the times I was poking before it’s there was a moment in which everybody said, hey, you’re just giving a negative opinion or you’re just saying words randomly, because you don’t have access to information. Now, today, you have whenever you look at using any device, you have access to information and see that Yeah, there is a lot of people who is focusing on the wrong type of information. So because of that is that I do recommend, if you’re not into that field, if if there is nothing that you have to do there, my suggestion is to step away from it. Because Yeah, it’s very easy to jump in that spiral in which you go in negativity. But it takes the same amount of strength or effort just not to jump into it.
Dr. Daniel Pozarnsky 14:20
Yeah, it’s really tough for me, like with Facebook being like a medical or like, you know, medical, medically trained doctor that to like, not get into like arguments with people because there’s so many things that are not correct, that are going around and, and I have to it does take effort to to not, you know, for me not to look at that or to not engage because people are kind of just going to believe what they want to it seems like a lot of times and every they can go up. There’s almost, I think we were talking about this last time, there’s almost too much information so they can always
Unknown Speaker 14:59
sort of look And then you’re just going to pick it. I’ll give you a very just just quickly, very ridiculous example yet it’s it’s an example that fits this. You go to school, you have some homework, doing some research about, I don’t know, history of the USA or history or whatever. You just go and google it history of Canada, for example. Enter. Yep, you’re not going to take a minute even to read different titles just to find if, if whatever the snippets being displayed by Google are suitable for what you what you need. It’s, it’s the traditional nature, that’s why it’s revenue. people focus on the in the first three. So I usually say it was number one or number two. Yep, yep. What makes you think that that is actually the information that you need, but is the one that you have? Ready? Right there immediately. It may work you don’t care, especially if you’re in school. And it fits, it works. You pass that’s it that that need of or that sense of urgency is something that is a little bit destructive maybe. And yeah, is not pushing you to research a little bit more. I mean, that’s my two cents.
Dr. Daniel Pozarnsky 16:28
I would totally agree with you because you know, as a business owner, like in me working or working on my marketing, we always want to be one are number one or number two on on Google. And there’s a lot of ways that you can do that. And not be legit. I’ve found and a lot of people just comes down to how much money they want to spend to get there. That’s not Those aren’t the best sources all the time. But they paid the most money to get to that spot or had the most resources to do it, basically.
Unknown Speaker 17:15
Oh, yeah. Yep.
Dr. Daniel Pozarnsky 17:17
Yeah. And and that that’s those are good sources either and like, I mean, even some of the sources that I trusted, like the World Health Organization, they, at the beginning of this Coronavirus, like they had said it’s not transmissible from human to human. They had things out like that and I have like how, how could they write something like that?
Unknown Speaker 17:44
Then with their relations of using the mask, same thing happens if you have to use the sanitizer, whether if it’s alcohol based or not, or if you can use each person a little glitch based program. Yeah,
Dr. Daniel Pozarnsky 17:59
please. Your house,
Unknown Speaker 18:00
and then you can do it with peroxide. And I don’t know. So it’s it’s, I believe that is something that this is the general consensus we know about viruses in general. Let’s focus on that right now. In the meantime, we dig in for more information and we will be updating down the road.
Dr. Daniel Pozarnsky 18:20
Yes, totally. Yeah, it was something like this. It’s gonna take years before they really get know what’s what it’s all like all the aspects of how it infects people and then how it spreads. And in Who is the most susceptible? I mean, generally we know but like, specifically, we don’t
Unknown Speaker 18:45
know effects are quite tricky. And even if you have them, under specific say that, I don’t know, you have to promote loss of weight. For example, in order for you to be less prone to struggle sequence of cobit a, you have to break the habit of 320 million people. Yeah, that’s not easy. It doesn’t matter how aggressive your campaign of yourself
Dr. Daniel Pozarnsky 19:16
Yeah, like that’s what that’s what, like you and me as doctors are up against all the time is trying to change people’s habits and and, and getting them to take baby steps in the right direction. and preventative care is what like I preach to people because I’m a chiropractor and we teach more. We teach more natural ways to preserve your body and to optimize it. More than like taking over the counter like painkillers or anti inflammatories for every you know Every piece of pain,
Unknown Speaker 20:02
and I do understand it, your patients may understand it, our patients may understand it, there is always going to be one that may be reluctant. And however, I believe as a general concerns is we know that there is medicine to fix. But nobody asked patients is focusing on medicine as prevention. And in my opinion prevention is is both cheaper, as well as an investment. Because you take care of yourself when you are 30 4050, that when you reach 70, or 75, you don’t have to feel like broke up because you need a new knee or a new hip or something like that. And whereas when you’re 50, and you’re not taking care of yourself and keep on that abuse, or let’s call it bad decisions, right, and then there’s you rich, no uncertainty To reach 55, or 60, and then you wake up and your knees cracking, or you can’t wake up properly, or when you sit down, you use you are actually able to sit down but not to sit up or to stand up. And so, and that is when people has, again, the sense of urgency to fix that. But it’s from the functional perspective, it’s late, and then you just have to. So, yeah, and things become expensive, and not only just to fix the issue, but on the mid to long term.
Dr. Daniel Pozarnsky 21:37
Yep, I that’s what I deal with every day, like people wait until they’re in pain, or they can’t function enough to do an activity that they love, like playing a sport or picking up their children or whatever their job may be, or they can’t do that and then they come in and they want to be fixed straightaway because they think chiropractors just you know, To set the bone back into place, and then be good to go, but that’s not how it works at all. Like we just improve the function getting, and we improve the function and the function of the body and that helps the structure. But that is a process was kind of interesting what you’re talking about, well, you got to take care of yourself when you’re 30 4051 of the things that I teach my can’t say physical therapy, but my not a physical therapist, and that’s a lot of the United States. 100 but my therapeutic exercise patients like when you stand up, don’t push off your knees, because because that’s a really bad habit to start you started when you’re about 30, but you learn not to fire your quads, your glutes, and 20 years from now, like your quads and your glutes are gonna be so tight and then your your hips are gonna wear out That’s how it starts. And a lot of people don’t know that. But that’s where I start with them. When we start physical therapy.
Unknown Speaker 23:07
Also, you focus on symmetry, you’re going to the store or offset the functionality on one. And then eventually your body will compensate on the other side and then not even in the midterm short term, you’re going to start experiencing issues with the opposite side. And or something else. So one problem, it’s becoming two, three, or maybe four.
Dr. Daniel Pozarnsky 23:32
Totally, I totally agree with that. And like, the thing that I talk about every day with my patients is like, you, your brain really can only recognize pain in one area of the body where it’s worse. So like, we’ll get someone’s neck feeling better than they’ll have low back pain, because their whole body’s been tight, and they’ll get the low back fix and then their hip hurts Yeah, Yeah, I get that is true. But we usually start with the the glute muscles and the muscles that control the hip to stabilize the, the lower back. A lot of people don’t know that, but it’s when those muscles stop working, that the back pain starts starts because the lower back muscles are much smaller than the glutes and they can’t stabilize the spine whereas, so then they start spasm and a lot of times people and they start spasming chronically tight, which compresses the joint, the, the disk, or the process or the joints on the back of the spine. And that will cause inflammation which causes the joint to break down all the times because it’s causing a cascade effect that That people just they don’t learn about that, you know, anywhere in our education. And so it’s teaching those things over and over reminding them. And prevention is, is the key to have a to having a healthy life, an active life and optimize life. And,
Unknown Speaker 25:22
yeah, there’s a cure for aging gracefully.
Dr. Daniel Pozarnsky 25:27
Yes, aging gracefully. I agree. Yes, I agree. And but it’s the same thing for Regenerative Medicine. You teach a lot of that? Correct? Yeah.
Unknown Speaker 25:39
Yeah, we have to focus a little bit on that. Assuming that there is a patient that comes here for with anti aging purposes, right. So in this one, our end is not just pushing stem cells and that said, Sure, they are coming here from the stem cells, but also part of the of the protocol is is providing this necessary information or, well, personalized information, but because your needs are not going to be the same as another one, another patient. And so we have to understand what is your diet? What are your goals? First of all, then what are your expectations? And then what can we do with the information that you’re providing us in order for us to try to not exactly teach you or maybe guide you to actually achieve your goals and or expectations. And that way, you are going to be building loyalty towards what we’re doing because it’s something although the concept of stem cells has about 10 years, maybe more. And from the therapeutic perspective, it’s something fairly new. So if you want your patients to trust in what you’re doing, you have to guide them properly in order for them to actually feel really good. And on dialysis is exactly what we tried to do not only the stem cells, but also providing you with information assistance phone calls, video calls in order for, I don’t know, one two months after the treatment, how you doing any questions, what have you been doing? And give me your feedback, right? And if you are not quite there yet where you want to be, let us understand where you are or how you’re feeling in order for us to realize what can be done and what cannot be done as well. And that is also the importance of our patients going back with their physicians because we cannot do the work. Let’s say telemedicine, we cannot we cannot do everything over the phone or over a videoconference. Yeah, because if our focus is preventing in order for the patient to be perfectly functional on their 70 or 80. They need also guidance over there wherever they live. So that’s that’s what we need this if not direct communication with the Doctors, we need cooperation of the patient going back with their doctors.
Dr. Daniel Pozarnsky 28:04
Yeah. So for instance, like if, let’s take for example, if I have a patient who has like a herniated disk, alright, or degenerated discs during a herniated disc, and in the United States, there’s limited options of what we think we can do for that like we do physical therapy, decompression therapy. And then usually that’s what I do in my office and that can alleviate a lot of the a lot of the a lot of the symptoms and help to dis heal a certain amount, but like it’s always been easy. How. So if we have a patient that usually doesn’t want to get therapy and are not going to be a surgery on their spine? How And they want to come to you come to you to get dental therapy on on a desk or on a degenerative joint. How would that work? How does it work?
Unknown Speaker 29:12
Well, first of all, as I said, knowing the expectations on how this situation of the patient is. Second, if they have some form of images, MRI, CT scan x rays doesn’t matter in order for us to have like, more like a visual on how the current situation or an updated situation, it’s of a patient, then I have to say that we have nothing against surgery, right? So we try to offer an alternative prior to surgery because we want at least that’s what I learned in medical school. Surgery should be the last step or the last research because if you go with surgery as the first option, there is always there risk to overlook some other alternatives. And especially in orthopedics, surgeries, there is some form of risk in which you are not going to fix the situation, maybe you’re, you’re just going to sort it out and then deal with whatever the outcome may be. Again, I have nothing against it. I have quite a few relatives of mine are actual spine surgeons, but they do it’s exactly that pushing away the concept of maybe focusing unnecessarily as much as possible. Now, what can we do or when it’s possible with this, if you are talking about degenerative disc disease or maybe some form of heavy aided disc, you know that there are levels of it. So, if we if we find out that the actual hernia, it’s compromising the function is causing way too much pain and is not responding with, let’s say, your approach. There is a possibility for us to consider suggesting, suggesting that patient an option of surgery. Why is this because if we are going to spend whatever amount of cash coming here having stem cells going back to you for when six 810 months of rehab or physical therapy or exercises, and the mechanical problem is still there, I rather anticipate to that and come clean with a patient, right? Because I’d rather have a happy potential patient than promising the elephant, the moon and the sun and flowers to a patient and that patient not to be happy in three or six months. And also, I don’t want you to lose a patient as well. So if if there is a patient, that it’s some form of a slight bulging disc or herniated, etc, etc. And we believe that we can inject the facets the perfectible muscles, Across the thoracic spine or the lumbar spine of the cervical spine, we will do it. However, we even write it down and handle this letter to the patient with some suggestions on our end on what they can start doing immediately have where it’s important for them to go back with you, because you just mentioned it a few moments ago, it’s important to sustain that stability of the spine by training the muscles. In some cases, if not you, most of the cases, the hernias or the degenerative diseases is because you think you have a strong back when you don’t. And you do not tend to to train your back because you if you keep the gym, you’re focusing on arms, you’re focusing on the bug you’re focusing on Yes, but you’re not focusing on the lower back. You’re not focusing on the upper back. You’re not focusing on your neck. You’re focusing on statics and looking good in the beach. Right? Yeah, but eventually and on the other hand,
Unknown Speaker 33:01
If
Unknown Speaker 33:03
you’re a an office type of person that you are sitting down for 678 hours, doesn’t matter how expensive your church is, you’re not training your back, you’re not giving some time to do some stretches, you are not giving some time to give some rest to your to your back. That’s why actually, if I’m not wrong, that is why this trend of using the standing desks came up because it’s important for you to every hour and a half if I’m not growing every hour or so, to stand out, maybe walk a little bit stretch, something like that. Something that another crazy guy named as or coined as office yoga or something like that.
Dr. Daniel Pozarnsky 33:50
Yep. Yeah, we have yoga. We have yoga in our clinic on Wednesday nights and Friday mornings actually.
Unknown Speaker 33:56
So and if it’s something that is going to impact Do this 20 year back awesome, because that’s what we needed. From the stem cell perspective, your body if the cells of your body are constantly releasing pro inflammatory agents or markers, right or signals, that is something that happens with the process of actually aging. So the more signals we release, the higher the damage and the higher the weakness or the less balance or homeostasis the body is going to find. So by injecting the stem cells locally, the one of the the abilities of the stem cells is sexually promoting differentiation into different adult muscle tissues. One of them is muscle strength muscle. So it’s possible for the stem cells to actually promote muscular formation or blood flow as well as muscle repair by themselves. But even if you just injected by an athlete, you need to train that area. And that is something that the stem cells cannot do by themselves. That is where we need, let’s say, in this case, your cooperation and also cooperation of the patient. So that way, instead of using the stem cells as a expensive bandit, the patient will actually feel and express improvements that are going to last more than maybe eight months or 10 months, perhaps much longer than that. Right? And once again, the idea is you are doing this investment in your health. Well, keep it it’s time for you to collect when you’re to harvest What do you just planted? Right? So it’s, it’s that stuff’s important thing, can it be done? Sure it can, but we also need your cooperation as
Dr. Daniel Pozarnsky 35:47
and as a patient like a patient needs to understand that by the time that you have a herniated disc, like your body has already compensated in, you know, three, four or five different ways to try to help you We need to rebalance. We need to rebalance your body after you get your stem cell surgery. And the movement also helps the new cells activating and grow I would imagine because movement equals life,
Unknown Speaker 36:19
too much home into this areas, remember what I was mentioning the signals, it’s like a GPS telling you where to go. So it’s pretty much the same thing. There’s the cytokines or markers or signals for the four different cells to act on them. So they’re the highest ability or the strongest property of stem cells is immune modulation. So they actually able to modulate the expression of pro inflammation or inflammatory markers, the most common one it’s, it’s known as i l six or interleukin six, and two more necrosis factor alpha, those are the the ones the two guys that are present in pretty much every form of inflammation in the body. Yeah, and if you want to cheaply measure them, there is another one known as
Dr. Daniel Pozarnsky 37:08
that’s when people hear about more because that’s they check for that diabetes quite a bit c reactive protein
Unknown Speaker 37:17
in our immune conditions, and even in people who have some form of arthritis, regardless what it is because it’s just a marker of inflammation. So if you even want to trace how you’re responding after a stem cells, even a simple test of silica
Dr. Daniel Pozarnsky 37:38
that will that will help you we are at
Unknown Speaker 37:42
the double so to know that you are actually responding to it. We perform a three treatments of reactive protein here and we leave the results to the patient. And let’s say when they will back to you and you are able to finish your therapy or not say 3456 months after Do you can prescribe another c reactive protein and they can see if the numbers are going up, or the numbers are plateauing or perhaps going down.
Dr. Daniel Pozarnsky 38:10
And then in the, in the in Mexico, as far as stem or regenerative medicine and stem cells, you can inject them like intro, intro dainius viously correct. And so with that, you can’t do that the United States would that help people with like diabetes energy people with like type one diabetes or type two for that
Unknown Speaker 38:34
specifically, or type one IV infusion of cells that there is this misconception that type two diabetes can be can can improve tremendously. And some, some people claim that it’s, it’s impossible here, but honestly, in type two diabetes is not exactly like that. One of the forms of stem cells is harvesting the stem cells from the fat right And this is the type of patients that I had this I had a stem cells from the fat and my diabetes type two, it’s pretty much cure, I can eat whatever I want. Not exciting. I mean, I am very sorry, I don’t want to be a party pooper and I don’t want to voice your bubble, but I will. Why is this basically, type two diabetes before you are depending on insulin is pretty much insulin resistance. And if you’re having a micro liposuction in order for whatever place to work with that fat, collect some form of stem cells and then using them to you, they have to remove 60 7080 100 cc of fat. So pretty much immediately or instantly, in 2030 minutes, you are losing 100 cc’s of fat. So you are reducing the insulin resistance. So that’s why plus the infusion of the system A vascular fraction, which is what you can get from the fat in about a couple of hours. You feel some improvements because you are pretty much losing some form of weight or in this case fat and improving the insulin usage, not not not the production, the actual using the swing that you’re producing. And therefore your results on your blog what is going to come pretty nice if you compare them with your previous ones. Yes, on the other hand, Type One Diabetes the the mesenchymal stem cells can be very helpful if or mostly if the patient is in something known as honeymoon phase, condiment phase. It’s a state in which the pancreas of that patient is still producing some insulin, even if it’s, let’s say, out of 100% of the bankers, even if you have 20% still producing some instruments should be enough for the stem cells to modulate the outer immune part, or the autoimmune triggered of the type one diabetes. And your body can somehow relearn to work with that 20% of pancreatic function in terms of insulin production. So that’s why those patients after having the stem cells, if we catch them in this in this phase, they can stay like that without needing days or depending on insulin or exogenous insulin for something between 10 months to a year up to maybe five or six years until the actual our immune part or the Oregon triggers too much bits, the anchors so you weren’t producing?
Dr. Daniel Pozarnsky 41:45
Yes, yeah, there’s a lot of people in their early 20s. They usually get a lot of people with type one diabetes unless you’re very young. They get diagnosed with Type two first and it’s really the pink there in that honeymoon phase where the pancreas is getting broken down. And then and then it can be in the late teens or the late like I had a friend who was, I don’t know, I suppose like 30 before she actually got the type one diagnosis. But it’s very expensive. After you have to start taking insulin every every day in United States, like, I get something like $2,000 a month for your insulin. So, stem cell therapy could be something that can be really helpful. If you catch it soon enough. It sounds like
Unknown Speaker 42:36
a case of a 40 year old kid that was diagnosed with Type One Diabetes. Fortunately, she responded well, unfortunately, they didn’t change the habits of the family. So the actual effects lasted for maybe six, seven months. On the plus side, she went from 30 units of insulin per day to zero for that period of time. But again, if you don’t change your habits, I mean, she’s 40 she pretty much with all due respect for the family. At 40 years old and 40 years of age, you have written no opinion whatsoever and in your house. So you you you do what your mom tells you to do, or you eat, what everybody’s eating, etc. So maybe it’s a family thing. I don’t know, I’m not questioning anything, but that’s the importance of us trying to convey is important principle in that particular patient to design some form of a special diet, maybe complex carbs, very small amount of complex carbs, non processed food, maybe staying away from everything that has refined flour or sugar or anything like that. No sodas and such etc. It’s like a sand is Kaylee I know exactly. And in order for the patient to pretty much feel healthy without Increasingly spending way too much insulin. If you catch them in these early stages
Dr. Daniel Pozarnsky 44:08
that’s really good to know. Because, yeah, if people could get treatment with stem cells and change their habits that could really be helpful for for people with in that honeymoon phase a type one, diabetes. I mean, I remember that, that we brought that up. Because, yeah, it’s tough once you get it once you have once you lose the use of your pancreas, and over time, it’s really hard on your body, all of your cells.
Unknown Speaker 44:43
There is also another side. That affects pretty much every patient when you are not able to perform, be act, eat. whatever other objective that I’m missing at the moment, the way you used to Do it before and that’s psychologically when do you use it yourself when we were asking about the herniated discs and whatnot, a, for example, a lady that likes gardening and then they cannot do any more gardening because the knee is Boston somehow. It may be slightly depressing because maybe she loves roses and she loves taking care of her darling Oh yeah, that she can’t
Dr. Daniel Pozarnsky 45:29
nakota and I have patients that are exactly like that they need our bone on bone or the hips. In a sense the knees and the hips. Were out in the neck can’t do that anymore. And then they’re more sedentary and they get morio or they have to go out to the United States. They wait too long actually to do the replacement and they wait so they waited almost five years too long. So then the other side your body has compensated too much and now the trend is like with me is that Just replaced both of them, like a two for one special and that’s just that’s really hard recovery and, and you’re not. You’re never the same again you lose range of motion. It’s hard to kneel still. So regenerative like stem cell therapy would be very helpful in that aspect.
Unknown Speaker 46:21
Yeah, they can, they can, as long as they have a little bit of cartilage left. They can the results can be can be very promising for them both in pain and function.
Dr. Daniel Pozarnsky 46:30
Yeah, your pain is the big thing too, because then they can’t sleep. And then that affects your whole body or your whole system.
Unknown Speaker 46:40
Does.
Dr. Daniel Pozarnsky 46:43
How much how much cartilage has to be left for successful stem cell treatment like your knee or your hip?
Unknown Speaker 46:55
usually don’t. There is not like a minimum amount of cartilage Then you need some form of cartilage in order for the source to hold in place and form some and attach to it, but
Unknown Speaker 47:09
you also need space. So if if this basis completely closed
Unknown Speaker 47:16
the stem cells stem can be useful but there is another concept that has to be taken in consideration and that is some form of decompression or surgical decompression in order for you to open up a little bit of space or make some space and then inject the cells locally. Our goal from the tourism point of view because we cannot do that in three or five days and that requires quite a longer amount of time. We try to catch them when they are complaining when there may be some osteophytes present in there. When maybe there is a slight robbing there is a lot of pain, maybe knee inflammation, physical, actual, visual information. We can do it if if the if they need Completely Robin, this still can be useful, but we do not address that here because both prices as they travel, the actual transportation of the patient and the time that the patient should be here is completely different. So it’s a completely different protocol that is slightly out of our hands because of the surgical part.
Dr. Daniel Pozarnsky 48:24
One of my patients as interesting. Okay, one of my patients will say they were thinking about a knee replacement. Usually they put it off if you want to get that. But if we did, let’s say we did decompression therapy on the knee along with rehab like for three months before they came to see you but that be enough time it’d be helpful to create that space.
Unknown Speaker 48:50
It’s just a matter to take literally to take a peek, an X ray or some form of image testing should be enough. As long as again as long as there is some space for us to push on for Are you?
Unknown Speaker 49:02
There are possibilities for it to
Dr. Daniel Pozarnsky 49:03
work, honestly. Okay, okay, that’s really good to know also. And then, in United States, like, a lot of people, not a lot of people, but I hear about people try or get it too late, the steps out there, but we think we can’t create as many stem cells here in our clinic as you can in your clinic. Because of the FDA regulations, we can’t grow or change the tissue outside the eye, we can expand the stem cells. So a lot of people will, you know, pay 510 thousand dollars and get it in their knee or hip when they’re 60. But again, they don’t do any therapy before the decompression that you’re talking about it like a doctor basically just gives him stem cells. He sends him underwear like I’ve never heard of The clinic that you know around our area at least that does any type of therapy afterwards they just you know recommend they just give them a shot and the stem cells that they were they get them here they get them from umbilical cord tissue from from baby some biologics labs. But those can’t be changed they but they don’t usually take in what happened studying because what we’re going to do like PRP therapy or start doing PRP therapy here in the next year or so and I’ve studied quite a bit and but the the, the by the biblical cord so from a lab that haven’t been changed, so it’s within FDA guidelines reject those, but it’s still not enough in terms of so the value of salaries Compared to what you can do, correct, is that correct?
Unknown Speaker 51:03
Yeah, yeah, you are somehow correct. I know some laboratories over there in the US that sell the cells that you are claiming that they’re mentioning. I know some other clinics that they perform bedside process of a quick bone marrow collection to treat the patients using the hematopoietic form of a stem cell or from the bone marrow and still inject them, they can actually achieve some some some good results. Again, quick disclaimer, I’m not bashing anyone. Actually, that’s not my objective. But it’s true. There are very few places that suggest come work to their patients, after they they spend $1 or 100,000. Doesn’t matter if you want. My personal idea or vision is that if you want a little bit of loyalty from your patient, Do you have to show other breed of care? Post treatment. So that’s, that’s why we cannot be completely behind them. But if we have some support of them through your through their doctors, that’s phenomenal. Because they have to achieve, they can achieve their goal, their goal by following let’s say the exercises that you provide is important. Yes, because of the same reasons that I mentioned earlier. You have to train your mind you have to push or to stress, let’s say that area into pushing your immune system to activate or to work or to to push the formation or the regeneration of that of that site. The stem cells alone by themselves. They can control inflammation, they can bring comfort in terms of pain, they can improve your overall health sensation. Sure, but if you don’t do anything else, if you don’t do you’re, you’re you’re you’re some changes in your life. What in your lifestyle sorry you will be remain you will be exactly the same person that is constantly bombarding your body with agents that promote inflammation whether it if it’s diet as ridiculous as it may sound, it could be diet could be but
Dr. Daniel Pozarnsky 53:18
I protect mission Yeah, yeah. Cuz the American diet they we have to say we cuz I don’t but like on average, like studies show that we 70% carbohydrates in our diet like we have that McDonald’s culture is slowly but too late I
Unknown Speaker 53:42
don’t have I have
Unknown Speaker 53:43
I have nothing against fast food because it’s convenient. It’s a nice cheat every once in a while but nobody’s forcing anyone to eat fast food every day which is a problem. So yeah, so because it’s convenient is quick Xion so Yeah, so we are focusing on convenience instead of health. So if, for example, if you eat McDonald’s four times a week here, because it’s cheap, I don’t know how much you can spend per person in McDonald’s, let’s say seven bucks, four times a week, it’s 30 bucks a week. And you you are saving going to a restaurant you’re saving, doing some groceries you’re saving on cooking, you’re saving on gas consumption, blah, blah. So maybe some cheaper but in your in your body, you’re just pushing the release of these inflammatory factors whether it’s through the stomach or while the flora, the gastrointestinal function, and this eventually is going to disturb your immune system. And if you add to it, that you have a bad knee, and then you’re eating this crap, everyday, everyday you will be gaining weight and you know that weight is not acceptable and excessive weight or obesity is not very good friends with new problems or ship problems? Oh, no.
Dr. Daniel Pozarnsky 55:02
That’s what people try to do once it’s too late, they try to start losing the weight in too late, you know,
Unknown Speaker 55:10
they may feel a little bit, okay. Right. But the problem is done. And now you have to work on two or maybe three different things. And not only that.
Dr. Daniel Pozarnsky 55:19
Yeah, exactly, exactly. But that’s where you can with stem cell therapy like you can start turning things around. Like, if you are, you know, motivated enough to do it, which, if you embed this in the therapy, like you should be motivated to change.
Unknown Speaker 55:41
And also if I may compliment that is the nature of doing the IV infusion of the cells. Not only the knee, the hip or the back of the neck. It’s it’s whatever the needed area, sauce, the IV infusion of the cells because IV fusion helps with that systemic inflammation.
Dr. Daniel Pozarnsky 56:03
Yeah, it just takes a total stress off of the body. So then it can work optimally. So those stem cells can grow and multiply, do what you want them to do or what the patient wants to do. Correct?
Unknown Speaker 56:18
Yeah. Again, the fact that you’re feeling okay or better, does not mean that you can do whatever you want. I mean, if you see it as an investment, you’re going to make a change. If you see it as a expense that you can do every, I don’t know, six or eight months. Okay, go ahead. But that’s not the point. Right?
Dr. Daniel Pozarnsky 56:37
Yeah, exactly. And that’s not most people don’t, you know, have the funds or resources to do stem cell therapy, you know, every six months unless you’re quite rich. Exactly. It’s not it’s not not necessarily cheap. But it’s, I would say death is cheaper
Unknown Speaker 56:58
than a hip issue. On a new hip
Unknown Speaker 57:03
but it both in cash and in sensation and in Aftermath and in a comfortable way. Well, if, again it I think that it depends on how the patient absorbs the actual value, not the cost but the value of of any medical procedure not only stances.
Dr. Daniel Pozarnsky 57:24
Yeah, like for myself, I’ve had actually quite a few surgeries because I like to play sports to be active and a little bit of adrenaline junkie. And each time I have about two knee surgeries and two shoulder surgeries and each time a daily daily. After a surgery though, the insurance will usually allow like six weeks of physical therapy, but really it takes a year to heal from from the surgery. And most people don’t know that. I tell my patients that too. So I always go work with specific trainers in Fargo and red Sanford policy. Shout out to them. They’re the best trainers and and the the best kept secret in town. I think that they’ve helped me a lot in the last 10 years as far as me being able to like, like do amateur boxing and mountain biking allowed me to keep doing those things and get back to running a little bit even though I do need to get systems out there BMI need to do that to the potential that I would like to what about disorders, there’s stem cell therapy. Let’s go back to the immune system a little bit because when lastly, we’re talking about how people that were affected negatively or they had a really hard time with the Coronavirus It affects your kidneys affects your heart protects your lungs that sometimes can actually help that and in some emergency situations can prevent that. Yes
Unknown Speaker 59:14
I will Coronavirus if you have if you’re positive to it, but no symptoms, we don’t suggest them. Right. However there there there is a group of or a population of patients that they are positive to the corner virus. And eventually they start to present symptoms that are related to acute respiratory distress syndrome in which they are having trouble breathing, getting oxygen in actually using or mobilizing that oxygen and that’s when they depend on being intubated. in that stage is what the cells are currently considered as a potential option, both to get out of the ICU as quick as possible instead of being there for too long Rubik’s and second perhaps leaving the hospital a quicker as well right. So, how in this particular phase or a stage how the cells work? There is something that the virus causes in the body that is known as cytokine storm. Pretty much the virus causes so much inflammation that releases I was mentioning earlier about the super active protein under interleukin six and the demonic Croesus factor alpha, well, the virus releases so much of those plus another three factors that it starts to cost something known as organic fair. So, does not matter how much asteroids or whether we’re trying hydroxy Klerk, quite a protein and some other immune suppressors and they were not having exactly the best results while in trying to suppress or to control this cytokine storm and that’s how eventually the cytokine storm comes down and it’s when the patient leaves ICU and it’s a survivor. And or I’m sorry for how they sound or the patient has a potential to die. So
Dr. Daniel Pozarnsky 1:01:16
currently the office like within a bath, that’s why, yeah, right.
Unknown Speaker 1:01:22
There are cases in which they start experiencing symptoms on day number 10. And by day number 12, they are already intubated one or maybe in 24 hours. Yeah. So So when they’re in that stage is what are the stem cells have both have actually proven to be useful to help control that cytokine storm. Therefore the patient is stays in the ICU for less time and actually moves out tu tu tu tu or no note ICU and then read it and then they are discharged. There is a clinical studies going on right now and in the US, we would like to work on something similar in here. But protocols and bureaucracies is slightly different here. And then over there, yeah. However, what can be done or what we can focus on and that this is my personal perspective on the what it’s coming about regenerative medicine, at least for the following six, maybe eight months. It’s helping or treating patients that are actual survivors of that stage of the Coronavirus. There are usually three parts or three things or areas that a patient can struggle with after having Coronavirus in such stage. One is cardiovascular problems that they tend to experience some thromboembolic events and there is a potential of having a stroke. Yep. We can treat patients with a stroke or They had a stroke, we’re using stem cells because the stem cell as I said before, stem cells have the ability to promote differentiation of blood vessels. So you can actually or the senses can actually push oxygen and promote some vascular formation in it’s known as the number area or the gray area in which the tissue is not completely gone, but is struggling for oxygen. And I think that some oxygen is better than oxygen. Right? Yeah. So So
Unknown Speaker 1:03:36
sighs
Unknown Speaker 1:03:38
right. It’s important and, and plus, you complement it with IV fusion of sales for production inflammation. That is that is being caused by the lack of oxygen flow. So that’s one second, the other part is the most important the most common which is pulmonary function. You a survivor of a Corona virus, it’s very likely that you can use or you may have some compromise between 10 up to 30% of pulmonary function. So you can actually notice it, because maybe you cannot go up the stairs as quick as before the event right. If you were intubated. It’s known currently due to the massive amount of studies that have been released. Thanks to Coronavirus that, thanks to a situation. You’re struggling for oxygen when you’re in ICU and the only way to push one oxygen is three two, right? However, the oxygen going in is not the problem but mobilizing it. So they truly being intubated with Coronavirus clearly not for every condition. I’m talking about Coronavirus. It may cost some form of fibrosis or inflammation or some other degree of compromise of the alveoli in the lungs. So, eventually, you will be inhaling, let’s say 1000 cc of air, but you will be working with 700. So, in this aspect, the IV fusion of the cells, it’s phenomenal because the first stop have the cells in the lungs, you’re putting the cells in the vein. And in order for those cells to reach the arteries, they have to go through the pulmonary network to from the venous blood to the to the arterial. And this this essentially home in the lung there is a nominal phenomenon known as luminary sequestration or center of sequestration pretty much is like a kidnapping or some of the cells in this area, because it’s a network and some of them may go stay there and the resume goes through.
Dr. Daniel Pozarnsky 1:05:54
That has to do with the different the different implant or the inflammatory markers are
Unknown Speaker 1:06:00
Yes, correct? Yes, for both mechanically and biomarkers, so eventually, the cells can actually reduce inflammation so the patient can actually improve somehow between five up to 15, maybe 20% improvement I function, very similar to the results that we have been noticing in patients with COPD. Now, and the other one, it’s some form of neurological problems and in some cases, small amount of kidney problems in which that is because the receptors of the of the virus is of the ACE to your answer. As to receptors, we have a lot of receptors in the kidneys as well. So there are some patients that may remain with some form of noodle neurological compromise such as nausea or trouble to smell and or or in Spanish this this future which is trouble for for tastes. properly and that God will prevail pretty much so I’m not saying that
Dr. Daniel Pozarnsky 1:07:08
that’s why they have that’s where the symptoms that no yes
Unknown Speaker 1:07:10
those that is one of the symptoms but depending how aggressive The situation is in the patient, there are patches that remained like that for three or four months or may remain like for a substantial amount of time. There are some patients that gain the smell and the taste back in couple of days.
Dr. Daniel Pozarnsky 1:07:29
So it must also have like some neurologic neurologic tissue receptors have abathur nerve and facial nerve return, actually,
Unknown Speaker 1:07:46
actually the h2 receptor, it’s present.
Unknown Speaker 1:07:51
When I went to school, we thought that we only had it in the lungs and in the heart. That’s why some sort of cardiac insufficiency which is another area where distances can come into play, and therefore pulmonary hypertension. And that’s where we were focusing the most, however, thanks to Coronavirus, I learned. I’m not saying that it’s something new but I learned that or we learned that we have Ace, Ace to receptors pretty much lungs, heart, intestines, kidneys, offertory ball, and I missing another spot. So that’s why the patients are experiencing ridiculous symptoms like no smell, or diarrhea. Yep. And they don’t pay attention to it. Maybe they just do some some some sort of component thing. But there is always a possibility for those symptoms to pretty much become nasty, and then you end up in the hospital. So
Dr. Daniel Pozarnsky 1:08:49
why does Why do you think like it’s, I think it’s less than 1% of people that actually have the cytokine storm. What What do you think predisposes them to that
Unknown Speaker 1:09:00
Well,
Unknown Speaker 1:09:03
what are the comorbidities? The most common one is obesity, blood pressure issues, heart condition. Those are the highest and diabetes, those are the most, especially if the diabetic patient is not treated correctly or taking the medication or treating themselves correctly, because you’re pretty much over exposing the receptors for the virus. So that’s the reason why in China and Italy, the the population that was considered to be or to die, let’s say the population that was dying the most was between 70 to 80. Yeah.
Dr. Daniel Pozarnsky 1:09:48
When when they’re in like, my North Dakota, I hadn’t heard of any younger people getting really sick.
Unknown Speaker 1:09:57
Yeah with for example, here in Mexico, the The population that the population that the population that it’s dying is between 35 to 45, maybe 50. And that is just because blood pressure issues, diabetes, and obesity, I don’t know if today, Mexico is number one or number two, in terms of obesity in the world, which is not something that we’re very proud of. But that is the reason why scientists are considering that, from 70 or 80 years of age over there in Asia and Europe here. We thought that it was going to be the same. But I know we overlooked a couple of things. And eventually, and that’s something that maybe happened in some spots in the US. and Europe was not that aggressive in in such productive ages. But here in Mexico and Latin America, was struck tremendously.
Dr. Daniel Pozarnsky 1:10:52
Yeah. Yeah, obviously, hypertension that are those are two the two of the symptoms That we were warned about to warn the patients. Do you think there’s a genetic factor involved? Or
Unknown Speaker 1:11:09
perhaps
Unknown Speaker 1:11:12
a genetic factor?
Dr. Daniel Pozarnsky 1:11:13
Yeah, cuz there’s no comorbidities but I guess there’s hours gotta be a comorbidity because like an actual person with a healthy, like most people survive and most people, like young people especially like they hardly notice that they get it. So there’s a lot of comorbidities that people don’t actually know that they have. And then they just say, Oh, you can’t you can just die suddenly, but there’s in a mess and like, usually always a reason. It’s kind of
Unknown Speaker 1:11:46
this deeper. And in some case, for example, the health personnel. There is a history of a nurse may have noticed that it used to be about to give their baby face dahlstrom guy, nurse, he got infected, and he had a really bad time. And physically he was phenomenal. But I don’t know if in such case or the cases of the health personnel
Dr. Daniel Pozarnsky 1:12:15
that ethically at least like that, at least look at aesthetic. Exactly.
Unknown Speaker 1:12:18
statically. Maybe physically, he was not exactly the best, but I don’t know. But I don’t know if it also has to do with the fact that health person that is in the COBie areas are constantly dealing with 3d with more than one patient. So I don’t know if there is some form of overexposure to be honest. I
Dr. Daniel Pozarnsky 1:12:38
yeah. Yeah, I would think that just fatigue and then there’s another thing I was just thinking about, like central nervous system fatigue that usually happens in people that like do like marathons like I’ve ran the five marathons in the past when I could run before but like Most of the people that are getting it also. And I wonder if it’s not because like their nervous system is run down, and they’re fatigued in that way, which affects the immune system. It’s just some ideas that I’ve had,
Unknown Speaker 1:13:15
besides even stress compromised your immune system. So you you any virus already, pretty much any disease just needs a small amount of a small window of opportunity to do its job. So, if if that’s what that’s why the at least my rationality behind the suggestion that I gave you what I mentioned to you earlier, stay away from the toxic that’s a new sort of this because there’s there’s always going to be one person that overstressed about pretty much everything. And then that is a huge factor, honestly.
Dr. Daniel Pozarnsky 1:13:56
Yeah, I totally agree with you on that. on that. Yeah, it seemed It was kind of funny like some people like we’re having riots here in the United States. Lately and and then people are like I thought COVID was over because we have riots going on.
Unknown Speaker 1:14:19
happened is that the riots on the whole? This movement? Exactly. Were bombarding the news so much that COVID went from this size to maybe this size because the riots was decisive. Yeah, so
Unknown Speaker 1:14:35
that tension is different.
Dr. Daniel Pozarnsky 1:14:38
There’s two more things that I wanted to talk about before we end the show tonight, like natural killer cells for cancer therapies and chemotherapy, or to help recover after chemotherapy. And then like exosomes, like, what are the exosomes used for exactly, that’s another thing that kind of can help
Unknown Speaker 1:15:02
Well, natural killer cell therapy quickly natural killer cell is a form of, of a white cell part of the innate immune system. So, the job of a natural killer cell, it’s pretty much checked on every single cell of your body. And they what they have to do is pretty much find a cell that it’s lazy without providing any functionality to the body or a cell that is compromised either by a virus or usually viruses. And so this this cells are known as senescence cells. So, all senescent a senescence cell is pretty much a cell that is just there without cheapening adult, right? So it’s just using space using resources, consuming resources, but not giving anything back. So My personal thinking about the nk cell therapy is the natural killer cells believe or follow the orders of the immune system that it’s cheaper for the immune system to get rid of the this senescent or unnecessary cells than keeping them alive. So by wiping them out, you’re pretty much keeping the actual functional cells. From the aging or anti aging perspective, this is something that it’s very useful because the lesson is in cells, the better the performance or the better the violence or him homeostasis of the body, regardless of the age in terms of cancer patients. It concerns a cancer cell system that tends to grow very quickly, depending on the form of cancer regardless if it’s benign, or or a malign type of tissue. Naturally, a cancer cell it’s so that, as I said, grow so quick that may outnumber Then your natural killer cells. So your nk cell is still doing its job, but they don’t have enough army to surround or control the issue. If you are exposed or overexposed, then it’s when the cancer gets bigger and bigger and bigger every now, nk cell therapy as cancer treatment is not a cure is mostly like the code you want, especially in early stages of cancer to contain the situation. In the meantime, those patients are having chemotherapy or radiotherapy or even a resection of the tumor. Right. It’s again it’s it’s an alternative, especially for those patients that don’t don’t like the concept of chemo or radio as well. And they have recently diagnosed with some form of cancer even if it’s a small one stage one very steady, not growing, etc etc. Perhaps you’ve heard you’ve heard this before. I don’t like medication because it’s too aggressive because it is chemotherapy, chemotherapy is very, very invasive, etc, etc. So, get nk cell therapy could be an option, right? In order to contain and in some cases to I’m not saying again curing but maybe limiting the tumor or the help the body fight exactly to find the production of this of the cells. That’s like the orbital conception of the treatment. It also can be of use for those patients with Lyme disease as long as long
Dr. Daniel Pozarnsky 1:18:44
a more common combination.
Unknown Speaker 1:18:46
Yeah, it’s very, very common and nowadays is very common. However, those those patients needs to be evaluated a little bit better because we’ve had different experiences positive and not so positive. I know like to say negative because every patient experience something positive. But some some patients experience really good things and some patients just thinks, right, yeah. It’s important to understand that the patient has some form of own immunity. It’s important to understand how the virus levels of the patients maybe and if the patient is actually diagnosed with Lyme disease. And now, in terms of exosomes, exosomes is something that is currently available somehow in the US because it’s not that regulated. But there is also a little bit of confusion about them. exosomes are pretty much a vesicle that is being released by a cell, one cell can release, let’s say 102, hundred exosomes. What it is, is pretty much the fusion of a cell compartment with the cytoplasm of the cell. So it forms a tiny sec that is released. Now. What it does Pretty much. exosomes are a form of hyper communication between cells. There are good exosomes and there are bad exosomes, even cancer cells can release bad exosomes, our objective is harvesting exosomes from the stem cells. When you have stem cells, there is something that takes place within the first two, maybe four days that is known as Peregrine effect. It’s a stage in which a patient feels really good. And they claim Hey, I feel fantastic. I have no pain, my autoimmune condition wherever it is, I barely feel it, etc, etc. Again, I don’t like to be the bad guy but don’t get overexcited. This is something known as parkour in effect. It means it may show you how you may feel on the long term, but it doesn’t mean that you’re going to feel exactly like that forever. So exosomes, it’s exactly the They are not to be to express the traffic factors are the markers that are part of the production effect. So pretty much for example, you can inject inject exosomes in in a articulation and the patient is going to feel really good, pretty much in three days, let’s say it’s the effects are quicker than with the stem cells, but they are not stem cells, they’re just going to bring some relief, the effects are going to be more immediate, what they will not represent some form of regeneration, like with the stem cells, it’s like, it’s like releasing the exosomes to pave the road for the stem cells. So, okay, there are patients that are very happy use using exosomes. Fantastic, if it works for you. That’s fine, right
Dr. Daniel Pozarnsky 1:21:58
but right now getting Is it more? Does it actually regenerate anything extra though? Or is it No, it does not
Unknown Speaker 1:22:05
do extra, some will not actually reject, they may push the release or they may modulate the inflammatory factors locally, and then your overall natural production of cells can do its job. Right? Well, that’s why I’m saying that they pretty much pave the road for your immune system to work better. And However, he also depends on your immune system, your natural production of cells and, and you’re correct, or the current health of the articulation or the area that you’re injecting exosomes in and so on now we’re in the recommendation is you’re having the exosomes in your articulation have the IV stem cells right because you that you need also the immune system modulation systemically. So overall, that is what exosomes are Right now, because of the size, they have very nice potential. And I’m pretty sure that in the future they are going to be used as vehicles to either for medication or for some other form of genetic engineering or something like that. Because they have the potential to improve communication between cells.
Dr. Daniel Pozarnsky 1:23:20
I’m really cute. I haven’t had a chance to study those a lot. But I question I want to, I want to know a bit more about two. Thank you for that. We’re about at the end of our time for the show today. Is there anything else you’d like to add about your clinic? Oh, I know you have a really you have a amazing concierge service. If when patients come down there for your treatments that you offer?
Unknown Speaker 1:23:50
Yes, actually, whoever is listening to this conversation and wants to know more about us. We have a free patient evaluation process. Again, I like to emphasize on the free part, because once again, a nice, I know that it’s going to sound repetitive, but everybody’s different. Therefore, needs are different. Therefore, if we’re talking about personalized treatment, the help has to be personalized as well. So we already provided you with a link. So anybody can get an r1. They can click on those links. Those things are going to guide. The people who’s inquiring about this to fill up? Quick question or the question is not for me, just because I’m nosy is mostly for me to understand the condition of the people who is asking information, right. It’s not that I don’t like to explain things in general, but general is not enough if we were talking about an individual. So once once we know What the issue or the condition of this patient is we communicate with them whether it’s over the phone or video conferences. I personally like video calls more because it makes them more personable. And also, I think that it helps to bring some level of trust at least. And if the patient Yeah, exactly you will, you will, when it’s when the first step of the relationship and we explained that the objective is mostly education is going through what they can expect, what they can, what they are going to feel, how the treatment takes place, where we are located, where the stem cells are coming from, we can I mean addressing their concerns, addressing travel concerns, etc, etc. So, once a patient is satisfied in terms of information, if the patient decides to move forward with the treatment, we have everything sorted for them, which Because as you said our concern department has to communicate with them to know if they have some special needs or not. Let’s say that something ridiculous I like I’m on the hook for example right and I haven’t been to Cancun Where can I get it? Don’t worry either we can set an appointment with a with a consumer services to take you to some organic grocery shopping if you want to. or
Dr. Daniel Pozarnsky 1:26:26
or therapy done I’m gonna I’m gonna have a bunch of really ridiculous requests on watermelon cut tiny chunk.
Unknown Speaker 1:26:41
by Apple that’s not
Unknown Speaker 1:26:44
because it happens. I mean there are patients that say hey, I like to cook my own food but the hotel doesn’t have a blender Can you help me with one? Sure. You know can go here is quite large that is like 16 or 17 miles of hotels. He was in Cancun. So there are hotels that are all inclusive. Their hotels are European service, European style or something like that. There are hotels, I have a full kitchen in them that where you can do whatever you want in terms of
Dr. Daniel Pozarnsky 1:27:13
Yeah, yeah, there’s
Unknown Speaker 1:27:16
I don’t think there are a lot of them. And because there are a lot of them. There are patients that say, I don’t know where to stay. So because he or she can can assist you with that. Yeah, that’s pretty obvious. It’s we try to, to provide peace of mind, which is one of the most important and expensive things,
Dr. Daniel Pozarnsky 1:27:37
especially since if I’ve never been there, you know, then that helped quite a bit.
Unknown Speaker 1:27:42
And also if you’re going overseas for therapy, yeah, that’s, that’s.
Dr. Daniel Pozarnsky 1:27:47
People get nervous about that.
Unknown Speaker 1:27:49
I don’t know. Great.
Dr. Daniel Pozarnsky 1:27:52
All right. Well, that wraps up our show for tonight. Thank you again for coming on are so Alberto and answering All right questions. I could talk about this for hours and hours. so fascinating field. Yeah, it’s fascinating and growing. So we appreciate appreciate your time and sharing with us what your knowledge very, very much. And we’ll get this out to as many people as we can so we can help him change as many people’s lives as possible.
